Look, culturally speaking, Hollywood isn't a kind place for business. I don't think that's a shock.
Some people say Ghostbusters isn't about anything. Others think it is quite obviously about starting a business. I think the gap here is that some people literally don't realize that being useful to others is satisfying, and this is a way to relate to your community in a positive way (insert obvious comment about why Hollywood would fail to notice this). At its core, entrepreneurship is always an emotional journey! Of course people would write stories about it. [And of course that explains why the EPA guy isn't the primary villain in Ghostbusters, because regulations aren't the primary antagonist of an entrepreneur – they're just annoying, obstacles that would be removed if people notice how useful you could be to them.] If it wasn't an emotional process, then there would be no employees, just contractors with business insurance. Call it complacent or risk-averse, or whatever, but taking an active responsibility for your own livelihood is a rare enough thing these days.
As a side note: Seinfeld is pretty transparently about how comedians get the premises for their stand-up bits. Very strange that people say it's about nothing when the framing device is so prominent. I'm not a Seinfeld superfan or anything, I just thought it was worth saying this.
But those themes, of starting a business, of the difficulties and how people can get in your way and at the end of the day all you want is to be useful and get a fair shake: those are at the heart of The Rising of the Shield Hero. Without spoiling anything, the first major story arc is about exploring a series of object lessons in Hayekian knowledge problems for would-be saviors. Rising of the Shield Hero and Ghostbusters are the few cases where someone is still the hero even though they condition their help on getting paid. Here, fairness is monitored very closely, and is definitely not the dynamic where the person with ability gives away everything to people in need, even when they spit on them.
These are stories about one of the most common human experiences, and I think we need more of them. People should know that, no matter how down on your luck you are, no matter how shunned or maligned, you can always be useful, and make your way by being useful, and finding fair but shrewd trades with others – and still be a hero.